Deputy Head of Process Development

12356 · Livingston, West Lothian
Department 12356
Employment Type Full-Time
Minimum Experience Experienced

Valneva is a specialty vaccine company focused on the development and commercialization of prophylactic vaccines for infectious diseases with significant unmet medical need. Valneva has leveraged its expertise and capabilities both to successfully commercialize two vaccines and to rapidly advance a broad range of vaccine candidates into and through the clinic, including candidates against Lyme disease, the chikungunya virus and COVID-19.


Valneva has operations in Austria, Sweden, the United Kingdom, France, Canada and the U.S. with over 700 employees.


To help support growth and development of our Vaccines we are actively looking for a Vaccine or Biologics Health Science focussed Deputy Head our of Process development Team. You will undertake the management of a highly experienced team of development scientists in the delivery of new vaccine products from early development into manufacturing. Technology Transfer, scale up, optimisation, implementation and GXP manufacture using technical and scientific expertise in the Vaccine / Biologics discipline. Further scale up / optimisation for robustness, consistency and yield for commercialisation. Provide site wide technical and investigational support through data evaluation and laboratory work. This is a high profile role with Global Valneva responsibilities and interactions at senior levels of the site and company.


Responsibilities

  • Manage and lead new vaccine product introduction by Technology Transfer. Ensure effective and timely new process establishment with a hands on approach
  • Lead multi-disciplinary project teams to ensure on-time initiation of clinical manufacture for new or upscaled vaccine products
  • Manage the GXP manufacture, closure and reporting of clinical vaccines, including cell banks, viral banks and vaccine batches through to sterile bulk Drug Product formulation
  • Identify and manage delivery of process development / improvement projects, from conception to validation, with a view to increased process robustness, yield and success rate or reduced COGs
  • Management of experienced senior scientists to ensure ownership and delivery of assigned project tasks, systems and areas of responsibility to agreed target dates
  • Provide technical expertise, troubleshooting and lead key technical investigations / assessments, utilising critical trended data to support on time delivery of Quality Investigations
  • Support regulatory submissions by provision or review of technical reports and/or data
  • Ensure development Proposals, Plans and Reports are generated with appropriate risk & commercial considerations, impacts and milestones for delivery, and aligned with business requirements and site projects, goals & objectives
  • To deputise for the Head of Function or other departmental colleagues as required
  • Deliver key critical data for the identification and mitigation of process risks or failure mechanisms through trending and escalation
  • Drive continuous process improvement and provide technical support to key site projects and business deliverables
  • Manage and track on time delivery of department owned Quality Management System actions and documentation
  • Represent the company to external contacts such as customers, suppliers and regulatory authorities for technical discussions
  • Lead by example in the development and maintenance of an enthusiastic, supportive and collaborative environment within the team, across the site and between sites
  • Shift work and out of hours work as required
  • To undertake any other duties as requested by the line manager in accordance with company requirements


Job Requirements

Experience:

  • PhD qualified preferable, or extensive additional relevant experience in Vaccines / Biotech discipline
  • Extensive experience (10+ years) of working within the Vaccine or Biologics Health Science Industrial sector, in Process / Assay Development, Manufacture or Analytical functions, particularly viral products
  • Proven track record in leadership of major, complex, time critical, multi-disciplinary projects involving diverse departmental teams
  • Proven Line Management capabilities of experienced Senior Scientists (5+ years)
  • Excellent understanding of protein chemistry and characterisation and their application to clinical manufacture processes
  • Strong GxP understanding and experience
  • Strong commercial awareness and demonstrable leadership
  • Good experience of statistical data analysis and process trending
  • Good experience of change management and risk analysis


Required Skills:

  • Excellent Scientific understanding of vaccines or protein chemistry through development, manufacture or analytics
  • Ability to confidently communicate at all levels of organisational structure
  • Excellent team management
  • Strong strategic prioritisation capability
  • Analytical thinking
  • Team player with awareness of impact on people, process and systems

Thank You

Your application was submitted successfully.

  • Location
    Livingston, West Lothian
  • Department
    12356
  • Employment Type
    Full-Time
  • Minimum Experience
    Experienced